Comparisons

Ozari vs Sequence for GLP-1: An Honest Comparison of Telehealth Options

If you're exploring GLP-1 medications for weight loss, you've likely come across both Ozari Health and Sequence. Both offer telehealth access to these powerful medications, but they take different approaches to pricing, medication options, and ongoing support. Understanding these differences can help you choose the service that best fits your health goals and budget.

Let's take an honest look at how these two programs compare, so you can make an informed decision about your metabolic health journey.

What Both Programs Offer

Ozari Health and Sequence are both legitimate telehealth platforms that connect you with licensed physicians who can prescribe GLP-1 medications. Neither requires in-person visits, and both ship medications directly to your door.

GLP-1 receptor agonists like semaglutide and tirzepatide work by mimicking hormones that regulate appetite and blood sugar. They've shown remarkable results for weight loss, with many patients losing 15-20% of their body weight when combined with lifestyle changes.

Both platforms handle the often-frustrating insurance and pharmacy navigation, though their approaches to medication sourcing differ significantly.

Pricing: Where the Biggest Difference Lies

This is where Ozari and Sequence diverge most dramatically.

Ozari Health Pricing

Ozari offers a straightforward pricing model starting at $99 per month. This includes your medical consultation, prescription, medication (compounded semaglutide or tirzepatide), and ongoing physician support. There are no hidden consultation fees or membership tiers to navigate.

The transparent pricing structure means you know exactly what you're paying each month without surprise charges.

Sequence Pricing

Sequence takes a different approach with a $49 monthly membership fee, plus the cost of medication on top of that. Depending on whether they're working with your insurance for brand-name medications or providing alternatives, your total monthly cost can range significantly—often $200-300+ per month when all costs are combined.

Sequence does offer insurance navigation services, which can be valuable if your insurance covers GLP-1 medications for weight loss. However, many insurance plans still don't cover these medications for weight management alone, leaving patients paying out-of-pocket anyway.

Medication Options and Sourcing

Both platforms can prescribe semaglutide (the active ingredient in Wegovy) and tirzepatide (the active ingredient in Zepbound), but they source them differently.

Ozari's Approach

Ozari primarily works with compounded versions of these medications from FDA-registered 503B facilities. Compounding pharmacies create customized medications that contain the same active ingredients as brand-name drugs but at significantly lower costs.

This is legal and medically appropriate when brand-name medications are in shortage—a situation the FDA has acknowledged for both semaglutide and tirzepatide. Compounded medications allow more people to access these life-changing treatments affordably.

Sequence's Approach

Sequence initially focuses on trying to get insurance coverage for brand-name medications like Wegovy or Zepbound. If insurance doesn't cover it or you don't qualify, they can provide alternative options, which may include compounded medications.

While working with insurance sounds ideal, the reality is that most insurance plans either don't cover GLP-1s for weight loss or have very strict BMI and comorbidity requirements. This can lead to delays in starting treatment while navigating prior authorizations.

The Clinical Experience

Both platforms connect you with licensed physicians, but the experience differs slightly.

Ozari emphasizes quick access to treatment with physician oversight throughout your journey. The intake process is streamlined, and most patients can start their medication within days of their initial consultation. Ongoing support includes access to your prescribing physician and dosage adjustments as needed.

Sequence offers a more insurance-focused navigation process, which includes working with your existing coverage. Their clinical team also provides support, though the experience may involve more waiting if pursuing insurance coverage routes.

For Women: What to Consider

Women make up the majority of GLP-1 users for weight loss, and there are some gender-specific considerations worth noting.

Women often experience more pronounced nausea when starting GLP-1 medications, especially during the first few weeks. Having quick access to your prescribing physician to adjust dosing can make a real difference in tolerating the medication.

Additionally, women going through perimenopause or menopause may find that metabolic changes make weight loss more challenging. GLP-1 medications can be particularly effective during this life stage, but having a program that doesn't delay treatment with insurance hurdles can be beneficial.

Men typically tolerate higher doses more quickly and may see faster initial results, though individual responses vary considerably regardless of gender.

What You Actually Pay: A Realistic Look

Let's be honest about total costs, because this matters when you're committing to a months-long treatment.

With Ozari, you're looking at $99/month, period. Over six months, that's $594 total.

With Sequence, if your insurance covers brand-name medication, you might pay the $49 membership plus whatever your insurance copay is—this could be excellent value if your copay is low. However, if insurance doesn't cover it (the more common scenario), you're paying $49 plus $200-400+ for medication, potentially $250-450+ monthly, or $1,500-2,700+ over six months.

The value equation depends entirely on your insurance situation.

Making Your Decision

Neither platform is inherently better—it depends on your specific situation.

Sequence might be the better choice if you have insurance coverage that's likely to cover brand-name GLP-1 medications, you're willing to navigate prior authorizations, and you don't mind potentially waiting longer to start treatment.

Ozari makes more sense if you want predictable, affordable pricing without insurance hassles, prefer to start treatment quickly, or already know your insurance won't cover GLP-1s for weight loss. The straightforward approach means fewer barriers between you and starting your health journey.

Questions to Ask Yourself

From the Ozari Care Team

When starting any GLP-1 medication, the most important factor isn't which telehealth platform you choose—it's consistency with the medication and lifestyle modifications. We see the best results in patients who stay on treatment for at least six months, stay hydrated, prioritize protein intake, and work up to their optimal dose gradually. The program you'll actually stick with is the right program for you.

Ready to Start Your Journey?

At Ozari Health we offer compounded Semaglutide and Tirzepatide starting at $99/month prescribed by licensed physicians and shipped to your door. Learn more at ozarihealth.com.

Medically reviewed by the Ozari Clinical Care Team, licensed physicians specializing in metabolic health and GLP-1 therapy. Last reviewed: April 29, 2026