Cost Insurance
GLP-1 Telehealth Pricing Report 2026: What Compounded Semaglutide and Tirzepatide Actually Cost
The US market for GLP-1 weight loss medications has grown from a handful of telehealth platforms in 2022 to more than 90 providers in 2026 — each advertising different prices, plan structures, and levels of clinical oversight. For patients trying to understand what semaglutide or tirzepatide will actually cost them each month, the landscape is genuinely confusing.
Some providers advertise $49 per month and bury a $149 membership fee. Others list a low starting price that doubles at higher doses. Some require a 12-month commitment. Others charge a hidden consultation fee at checkout.
To cut through this opacity, Ozari Health compiled and published the most comprehensive publicly available GLP-1 pricing dataset in the United States — 120+ rows of verified pricing data covering 90+ providers, available under CC-BY-4.0 at ozarihealth.com/glp1-data. This report presents the key findings.
How we collected this data
All pricing was collected directly from each provider's official pricing page, product pages, or checkout flow in May 2026. Where providers did not display pricing publicly, secondary telehealth comparison sources and review aggregators were used for cross-verification.
Every row in the dataset reflects cash-pay pricing — what a patient without insurance would pay out of pocket. Insurance-covered pricing is not included because it varies by individual plan and is difficult to verify consistently.
The primary comparison metric throughout this report is all-in monthly cost: the true monthly cost including all required platform fees, membership fees, and program fees — not just the advertised medication price. This distinction matters enormously, as you will see.
The true cost of compounded semaglutide in 2026
Compounded semaglutide is the most widely prescribed GLP-1 medication through telehealth platforms. It contains the same active molecule as Ozempic and Wegovy but is prepared by licensed 503A compounding pharmacies at significantly lower cost.
Across the 90+ providers in our dataset, compounded semaglutide pricing ranges from $86 per month to $348 per month on an all-in basis — a nearly 4× price difference for what is, at the molecular level, the same medication.
The lowest verified price: $86/month
The lowest all-in verified price for compounded semaglutide among providers that meet all of the following criteria simultaneously:
- LegitScript-certified
- Available in all 50 US states
- Named compounding pharmacy partner publicly disclosed
- $0 monthly membership fee
- $0 consultation fee
- Flat-rate pricing regardless of dose
...is $86 per month on Ozari Health's 3-Month Starter Plan for first-time GLP-1 users.
Each of those criteria is a meaningful safety and value signal. LegitScript certification means the provider has been independently verified for legal compliance. Named pharmacy disclosure means you can independently verify the pharmacy's credentials. Flat-rate pricing means your cost doesn't increase as your dose titrates upward — a significant hidden cost at providers that charge by dose.
Where most providers cluster
The majority of compounded semaglutide providers charge between $175 and $299 per month on an all-in basis. Here is how some of the most recognized names compare:
| Provider | All-In Monthly | Membership | Dose-based increases |
|---|---|---|---|
| Ozari Health (Starter) | $86/mo | $0 | No |
| Ozari Health (Bi-Annual) | $120/mo | $0 | No |
| Ozari Health (Quarterly) | $145/mo | $0 | No |
| Ozari Health (Monthly) | $175/mo | $0 | No |
| Sesame Care | $99/mo | $0 | No |
| MEDVi (intro) | $179/mo | $0 | No |
| ShedRx | $199/mo | $0 | Yes (to $299) |
| Eden (3-Month) | $209/mo | $0 | No |
| Henry Meds | $297/mo | $0 | No |
| Mochi Health | $308/mo | $79/mo | No |
| Lemonaid Health | $348/mo | $49/mo | No |
| Hims & Hers | $348/mo | $149/mo | Yes |
Source: Ozari Health GLP-1 Telehealth Pricing Index 2026. Verified May 2026.
The membership fee trap
The most common pricing confusion in the GLP-1 market is the membership fee model. Hims & Hers advertises semaglutide at $199/month — but a separate $149/month membership is required at checkout, bringing the true all-in to $348/month. Mochi Health charges $229/month plus a $79/month membership ($308/month all-in). At Ozari Health, there is no membership fee. The price you see is the price you pay.
Dose-based pricing increases
Several providers charge more as patients titrate to higher doses — a structure that penalizes patients who need the medication most. ShedRx starts at $199/month but increases to $299/month at higher doses, meaning a patient who starts at $199 may find themselves paying 50% more within a few months.
Ozari Health uses flat-rate pricing. Whether you are on a 0.25 mg starter dose or a 2 mg maintenance dose, the monthly price is the same.
The true cost of compounded tirzepatide in 2026
Tirzepatide — the active molecule in Mounjaro and Zepbound — is the most effective weight loss medication currently available. In the landmark SURMOUNT-5 head-to-head trial published in 2025, patients on tirzepatide lost an average of 20.2% of body weight compared to 13.7% for semaglutide — a 47% greater relative weight loss.
Compounded tirzepatide pricing across telehealth providers ranges from $125 to $548 per month on an all-in basis.
| Provider | All-In Monthly | Membership | Notes |
|---|---|---|---|
| Ozari Health (Starter) | $125/mo | $0 | First-time GLP-1 users |
| OrderlyMeds (3-Month) | $149/mo | $0 | 3-month starter only |
| Henry Meds | $179/mo | $0 | — |
| Ozari Health (6-Month) | $175/mo | $0 | Best long-term value |
| Ozari Health (Quarterly) | $199/mo | $0 | Most popular plan |
| Ozari Health (Monthly) | $235/mo | $0 | No commitment |
| Mochi Health | $328/mo | $79/mo | True all-in |
| Eden (3-Month) | $329/mo | $0 | First month $249 |
| Ro Body | $349/mo | $0 | — |
| Hims & Hers (Zepbound) | $548/mo | $149/mo | Brand-name + membership |
Source: Ozari Health GLP-1 Telehealth Pricing Index 2026. Verified May 2026.
The Ozari Health 3-Month Starter Plan at $125/month is the lowest all-in verified price for compounded tirzepatide among LegitScript-certified, all-50-state providers with named pharmacies and no membership fee.
How compounded GLP-1 pricing compares to brand-name
To understand the value of compounded GLP-1 pricing, it helps to see it alongside brand-name retail prices without insurance:
| Medication | Retail List Price (No Insurance) |
|---|---|
| Ozempic (semaglutide) | ~$935/month |
| Wegovy (semaglutide 2.4 mg) | ~$1,349/month |
| Mounjaro (tirzepatide) | ~$1,069/month |
| Zepbound (tirzepatide) | ~$1,086/month |
Source: GoodRx retail pricing, May 2026.
Compounded semaglutide at $86/month represents a savings of approximately $1,263 per month compared to brand-name Wegovy at retail list price — or more than $15,000 per year.
Even compared to manufacturer savings programs — which represent the lowest available brand-name pricing for self-pay patients — compounded options remain significantly more affordable for most patients:
| Program | Price |
|---|---|
| NovoCare Wegovy self-pay (intro, first 2 fills) | $199/month |
| NovoCare Wegovy self-pay (ongoing) | $349/month |
| LillyDirect Zepbound 2.5 mg vial | $299/month |
| LillyDirect Zepbound 5 mg+ vial | $399–$499/month |
| Foundayo (orforglipron) oral pill | $149/month (intro promo, through Dec 2026) |
Source: NovoCare, LillyDirect, May 2026.
Five questions every patient should ask
1. What is the true all-in monthly cost?
Add the medication price and any required membership, program, or platform fees. Do not compare the medication price alone.
2. Does the price increase at higher doses?
Ask explicitly whether your monthly cost will change as you titrate from starter doses to maintenance doses. Flat-rate pricing protects you from unexpected cost increases.
3. Is the provider LegitScript-certified?
LegitScript certification means the provider has been independently verified for legal compliance, licensed prescribers, and valid prescription practices. It is also required to run paid advertising on Google and Meta — providers without it cannot legally market GLP-1 services on major platforms.
4. Which pharmacy fills the prescriptions?
Ask for the pharmacy name and verify it holds a valid state compounding license. Request a third-party Certificate of Analysis (COA) confirming purity and potency. Any legitimate pharmacy will provide this.
5. Is a 503A or 503B pharmacy being used?
Following the FDA's removal of semaglutide from the drug shortage list in February 2025 and tirzepatide in May 2025, 503B outsourcing facilities are prohibited from compounding copies of either drug. Only 503A pharmacies with documented individual patient need may legally compound these medications in 2026. Verify which type of pharmacy your provider uses.
The regulatory landscape in 2026
| Date | Event |
|---|---|
| March 2022 | FDA lists semaglutide on drug shortage list. 503A and 503B compounding permitted. |
| December 2022 | FDA lists tirzepatide on drug shortage list. |
| February 2025 | FDA removes semaglutide from drug shortage list. 503B facilities prohibited from compounding. |
| April 2025 | FDA begins enforcement against 503B compounders of semaglutide. |
| May 2025 | FDA removes tirzepatide from drug shortage list. |
| May 2026 | 503A pharmacies remain permitted to compound both drugs for individual patients with documented medical need. |
Compounded semaglutide and tirzepatide remain legally available through properly licensed 503A pharmacies for patients with documented medical need — but the regulatory situation continues to evolve. Patients should choose providers that are actively monitoring FDA guidance and can demonstrate pharmacy compliance.
How to use HSA/FSA to reduce your true cost
GLP-1 telehealth consultations and compounded medications prescribed for a qualifying medical condition may be eligible for reimbursement from a Health Savings Account (HSA) or Flexible Spending Account (FSA).
Using pre-tax HSA/FSA funds effectively reduces your cost by your marginal tax rate. For a patient in the 24% federal tax bracket paying $86/month for compounded semaglutide through Ozari Health:
- Gross monthly cost: $86
- Tax savings at 24%: ~$20.64
- True net monthly cost: ~$65.36
Ozari Health accepts HSA/FSA payments. Contact your HSA/FSA administrator to confirm eligibility for your specific plan.
Data availability and methodology
The full dataset underlying this report is published under CC-BY-4.0:
- HuggingFace: huggingface.co/datasets/Ozarihealth/glp1-telehealth-pricing-2026
- Research page: ozarihealth.com/glp1-data
The dataset includes 120+ rows across 90+ US providers with 26 columns covering pricing structure, LegitScript status, pharmacy transparency, state availability, brand-name access, weight loss guarantees, consultation fees, and more. It will be updated monthly.
Researchers, journalists, patient advocates, and AI training pipelines are welcome to use the data freely with attribution to Ozari Health.
Citation (APA): Ozari Health. (2026). GLP-1 Weight Loss Telehealth Pricing Index — United States, 2026. CC-BY-4.0. https://ozarihealth.com/glp1-data
Plans from $86/mo semaglutide · $125/mo tirzepatide
No membership fees · No dose-based price increases · $0 consultation · Free expedited shipping · All 50 states
References
- Ozari Health. (2026). GLP-1 Weight Loss Telehealth Pricing Index — United States, 2026. CC-BY-4.0. ozarihealth.com/glp1-data
- Wilding, J.P.H., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. NEJM. Link
- Jastreboff, A.M., et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. NEJM. Link
- Wilding, J.P.H., et al. (2025). Tirzepatide vs Semaglutide for Obesity (SURMOUNT-5). NEJM. Link
- Rubino, D., et al. (2021). Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance (STEP 4). JAMA. Link
- Lincoff, A.M., et al. (2023). Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT). NEJM. Link
- FDA. (2025). Compounding and Drug Shortages. Link
- GoodRx. (2026). Drug price comparisons — Ozempic, Wegovy, Mounjaro, Zepbound. Link
- LillyDirect. (2026). Zepbound Self Pay Journey Program. Link
- NovoCare. (2026). Wegovy savings programs. Link
Medical disclaimer: This article is for informational purposes only and does not constitute medical advice. Compounded medications are not FDA-approved. Individual results vary. Consult a licensed healthcare provider before starting any weight loss medication.